See what you missed at USCAP 2024: Innovation in digital pathology workflows for IHC & FISH and advancing HER2 scoring accuracy.

Immunohistochemistry

Immunohistochemistry (IHC) is a technology and a process of selectively evaluating antigens (e.g. proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues. IHC staining is widely used in the clinical diagnosis and basic research to study abnormal cells such as those found in cancerous tumors. Usually, visualizing an antibody-antigen interaction can be accomplished in a way that an antibody is conjugated to an enzyme that can catalyze a color-producing reaction.

  • ADH5
  • Adrenocorticotropic Hormone
  • AE1/AE3 (Pan Cytokeratin)
  • AFP
  • Alpha 1-Antichymotrypsin
  • Amyloid A
  • Amyloid A&P Panel
  • Amyloid P
  • ALK, D5F3 (Lung, FDA)
  • Annexin A1
  • Arginase 1
  • B72.3
  • Ber-Ep4
  • Beta Catenin
  • CA125
  • CA19.9
  • Calcitonin
  • Calponin
  • CAM5.2
  • Carbonic Anhydrase IX (CA IX)
  • Caretinin
  • CD31
  • CD44
  • CD99
  • CDK4
  • CDX2
  • CDX2/CK7 Double Stain
  • CEA (M)
  • CEA (P)
  • Chromogranin A
  • CK5/6
  • CK7
  • CK19
  • CK20
  • Collagen IV
  • D240
  • Desmin
  • DOG1
  • E-Cadherin
  • Factor VIII
  • Factor X111a
  • FSH
  • Gastrin
  • GATA3
  • GCDFP15
  • GFAP
  • GH
  • Glucagon
  • GLUT1
  • Glypican-3
  • HBME1
  • HCG Beta
  • HepPar1
  • HMB45
  • HPL
  • IDH1
  • Inhibin
  • INI1
  • Insulin
  • LH
  • Mammaglobin
  • MART-1
  • MDM2
  • Melan A
  • Mesothelin
  • MITF
  • MOC31
  • MYOD1
  • Myogenin
  • Myoglobin
  • Napsin A
  • NF (Neurofilament)
  • NSE
  • p16
  • p27
  • p40
  • p53
  • p57
  • p63
  • p120 Catenin
  • p504S
  • PAX8
  • PD1
  • Perforin
  • PHH3
  • PLAP
  • Prolactin
  • PSA
  • PSAP
  • PSMA
  • PTH
  • RCC1
  • S100
  • S100p
  • Serotonin
  • Smooth Muscle Actin
  • Somatostatin
  • SOX10
  • STAT6
  • Surfactant
  • Synaptophysin
  • Thyroglobulin
  • Thyroid Stimulating Hormone
  • TTF1
  • Vimentin
  • WT1
  • CDX2/CK7
  • E-Cadherin/p120
  • p63/CK5/6
  • PIN4
  • TFF1/Napsin A
  • Uro-2TM (CK20/p53)/CD44
  • PD-L1 22C3 (FDA) (for KEYTRUDA®)
  • Cervical
  • ESCC (Esophageal)
  • Gastric/GEA
  • HNSCC (Head & Neck)
  • NSCLC
  • Urothelial Carcinoma
  • PD-L1 SP142 (FDA) (for TECENTRIQ®)
  • NSCLC
  • TNBC (Breast)
  • Urothelial Carcinoma
  • PD-L1 28-8 (FDA) (for OPDIVO®)
  • PD-L1 SP263 (FDA) (for IMFINZITM)
  • pHistone H3 (PHH3)
  • PTEN
  • Retinoblastoma Protein (RB)
  • RRM1
  • TOPO1
  • Thymidylate Synthase
  • VEGF
  • Adenovirus
  • CMV (IHC)
  • CMV (ISH)
  • EBER (ISH)
  • H. Pylori
  • HHV8
  • HPV RNA (ISH)
  • HSV 1/2
  • Parvovirus
  • Pneumocystis
  • Spirochete
  • Toxoplasma
  • VZV
  • ALK1
  • Annexin A1
  • BCL2
  • BCL6
  • BOB1
  • BRAF V600E
  • C-MYC
  • CD1a
  • CD2
  • CD3
  • CD4
  • CD5
  • CD7
  • CD8
  • CD10
  • CD15
  • CD20
  • CD21
  • CD23
  • CD25
  • CD30
  • CD33
  • CD34
  • CD42b
  • CD43
  • CD45 (LCA)
  • CD45RO
  • CD56
  • CD57
  • CD61
  • CD68
  • CD79a
  • CD117/cKIT
  • CD123
  • CD138
  • CD163
  • Clusterin
  • CXCL13
  • Cyclin D1/BCL1
  • EMA
  • Fascin
  • Glycophorin A
  • Granzyme B
  • Hemoglobin A
  • IgA
  • IgD
  • IgG
  • IgG4
  • IgM
  • Ki67 (MIB1)
  • Lysozyme
  • MPO
  • MUM1
  • OCT2
  • OCT4
  • PAX5
  • SOX11
  • TCL1
  • TCR BetaF1
  • TdT
  • TIA1
  • TRAP
  • Tryptase
  • ADH5
  • E-Cadherin
  • ER
  • Her-2 Breast
  • Ki67 (MIB1)
  • Mammaglobin
  • PR
  • Mismatch Repair Panel (MLH1, MSH1, MSH2, PMS2)
  • MLH1
  • MSH1
  • MSH2
  • PMS2
  • CMV (ISH)
  • EBER (ISH)
  • HPV RNA (ISH)
  • Kappa/Lambda
  • Double Esterase
  • Myeloperoxidase
  • PAS
  • Sudan Black B
  • AcP
  • AFB
  • Alcian Blue
  • Calcium Stain
  • Colloidal Iron
  • Elastic Stain
  • FITE
  • Fontana Masson
  • Giemsa
  • GMS
  • Gram Stain
  • Iron
  • Mucicarmine
  • PASD
  • PASF
  • Reticulin
  • Trichrome
  • Warthin Starry
  • Wright Giemsa