Hematopathology

We offer comprehensive hematopathology services, including expert second opinion consultations and start-to-finish bone marrow procedures supervised by hematopathologists. We accept peripheral blood, bone marrow, lymph nodes, fresh tissue biopsies, body fluids, fine needle aspirates and formalin fixed paraffin embedded specimens for hematopathology testing.

Through our 20/20 Core Evaluation option, our board certified cancer experts can determine the medically necessary testing for your patient. By ordering the 20/20 Core Evaluation option, providers can expect to receive 1 concise pathology report that summarizes morphology, flow cytometry, fluorescence in situ hybridization (FISH), cytogenetics and molecular test results for a more streamlined hematopathology approach.

See below for more details on our hematopathology methodologies and test services:

  • Pathology Consultation with Morphologic Interpretation and/or Ancillary Studies (Flow Cytometry, Routine Chromosome Analysis, FISH, PCR and/or NGS); if clinically indicated.
  • Acute Leukemia Panel (Usually performed on bone marrow/peripheral blood. Acute leukemia panel includes lymphoma markers.)
  • Lymphoma Panel (Usually performed on tissue and fluid.)
  • CLL Prognostic Panel
  • Immunodeficiency Panel
  • PNH Panel
  • Myeloma Panel
  • Routine Chromosome Analysis
  • Specimen Culture and Hold
  • ALL
  • AML
  • CLL
  • CML
  • Myeloma
  • MDS
  • Eosinophilia
  • High-Grade/Large B-Cell Lymphoma
  • B-Cell NHL Panel
  • Specimen Culture and Hold
  • ALK/Lymphoma (2p23)
  • ATM (11q22)
  • BCL6 (3q27)
  • BCR-ABL1/ASS1 t(9;22)
  • CBFB/MYH11 inv(16)
  • CKS1B/CDKN2C (1p/1q)
  • ETV6/RUNX1 t(12;21)
  • FGFR1 (8p11)
  • IGH (14q32)
  • IGH/BCL2 t(14;18)
  • IGH/CCND1 t(11;14)
  • IGH/FGFR3 t(4;14)
  • IGH/MAF t(14;16)
  • IGH/MYC t(8;14)
  • MALT1 (18q21)
  • KMT2A (MLL; 11q23)
  • MYC (8q24)
  • PDGFRA (4q12)
  • PDGFRB (5q32)
  • PML/RARA t(15;17)
  • RUNX1T1/RUNX1 (ETO/AML1) t(8;21)
  • TP53 (17p13)
  • 5q-/-5
  • 6q21/6q23
  • 7q-/-7
  • +8
  • +12
  • 13q-/-13
  • 20q-
  • POC Ploidy: FISH on Formalin Fixed Products of Conception, Common Trisomies and Triploidies, Chromosomes 13/16/18/21/X/Y
  • Hematology Profile (DNA) (177 genes)
  • Hematology Fusion Profile (RNA) (68 genes)
  • Hematology Profile Plus Fusion (DNA and RNA)
  • DNA Extraction and Hold
  • JAK2 V617F Mutation
  • MPN Molecular Panel (JAK2 V617F, JAK2 exon 12-14, CALR, and MPL Mutation Analysis)
  • JAK2 exon 12-14 Mutation
  • CALR Mutation
  • MPL Mutation
  • BCR-ABL1 p210/p190 (PCR - Quantitative)
  • MYD88 L265P Mutation
  • FLT3 Mutation
  • FLT3/NPM1 Mutation
  • NPM1 Mutation
  • PML/RARA (PCR)
  • IDH1 and 2 Mutation
  • SF3B1 Mutation
  • B-cell Clonality
  • T-cell Clonality
  • IgVH Hypermutation
  • BRAF V600E Mutation
  • STAT3 Mutation
  • CEBPA Mutation
  • ABL1 Kinase Domain Mutation
  • ASXL1 Mutation
  • BTK Inhibitor Acquired Resistance Panel (BTK and PLC-gamma2)
  • BTK Mutation (C481S Mutation and Others)
  • CXCR4 Mutation
  • EZH2 Mutation
  • KIT D816V Mutation
  • KRAS/NRAS Mutation
  • MLL-PTD Mutation
  • SRSF2 Mutation
  • TET2 Mutation
  • U2AF1 Mutation
  • ZRSR2 Mutation