Hereditary Cancer

Approximately 10% of certain cancer types are inherited in nature. Inherited pathogenic variants in certain genes may increase an individual’s risk of developing cancer(s) during their lifetime. For example, individuals carrying pathogenic variants in BRCA1 and BRCA2 genes are at significantly increased risk of developing breast, ovarian, prostate, pancreatic and other cancers with varying age of onset. CorePath offers next generation sequencing (NGS)-based genetic testing to identify pathogenic single nucleotide variants (SNVs) and copy number variants (CNVs) in cancer predisposition genes associated with breast cancer, ovarian cancer, colorectal cancer, Lynch syndrome, and neuroendocrine disorders. We also provide genetic counseling services before and after the genetic testing to the patients.