Cancers are genetically heterogeneous diseases. Understanding the biology of different tumor types is critical for an effective diagnosis and treatment. Altered gene expression, single nucleotide variants (SNVs), copy number variants (CNVs), gene fusions and other gene rearrangements play a role in the pathogenesis of different solid tumors. CorePath offers a combination of immunohistochemical, FISH, quantitative real time PCR, and next-generation sequencing (NGS)-based tests for somatic variant detection in each cancer type.